YABANMERSİNİ (VACCİNİUM MYRTİLLUS L.) MEYVE ÖZÜ'NÜN MİDE KANSERİ, AGS HÜCRE HATTI ÜZERİNDE ANTİOKSİDAN AKTİVİTESİ VE ANTİ-KANSER ETKİLERİ

Objective: Vaccinium myrtillus L. fruits are consumed as food. This research was aimed to evaluate V. methanol extract antioxidant and cytotoxic activities determine its anti-cancer potential further study against gastric cancer. Material Method: fruit (Bilberry) examined for by ABTS•+ DPPH• assays. The phytochemical analysis of the studied HPLC method. effect on cancer cell line AGS measured Cell Titer-Glo assay. Additionally, healthy control, fibroblast like human mesenchymal stem used testing efficacy. Result Discussion: showed 0.1413 0.0439 mg/mL IC50 values activity assays, respectively. Malvidin-3-O-Glucoside detected an anthocyanin compound Cytotoxicity that among different concentrations (0.5-10 mg/ml), most significantly, 2 mg/ml Bilberry treatment decreased viability cells while sparing MSC cells. data suggests several lines well determination a active substance in extract.